尊敬的各位同道，
蛋白质SUMO、Ubiquitin和Ubiquitin-likeProtein修饰是近十年来生命科学研究的一个热点领域。备受瞩目的本领域的一个国际盛会“8th InternationalConference on SUMO, Ubiquitin, UBL Proteins: Implication for HumanDiseases”将于10月21-23日在上海交通大学医学院举行。该会议每两年举行一次，将邀请来自全世界本领域的顶级科学家报告他们的研究成果，并讨论本领域的发展方向。今年的会议将由上海交通大学医学院院长陈国强院士和该会议的创始人EdwardYeh教授共同组织。这次会议邀请到了Nobel laureates Aaron Ciechanover教授和AvramHershko教授以及本领域的国内外科学家来进行大会报告。这次会议亦将会让全世界了解中国该领域的发展，并推动中国科学家与国际上该领域的科学家之间开展广泛地交流与合作。
在大会召开期间，您将有机会与全世界该领域的著名科学家进行面对面的交流并讨论本领域的进展以及将来的发展方向。
了解有关大会详情及注册请通过大会网站：http://sumo2016.shsmu.edu.cn/
如果需要任何帮助，请联系：
张哲宁
Tel/Fax： 21-64661525
Email: zhangzhening@shsmu.edu.cn
我们期待你来参加这次盛会。
这是SUMO和Ubiquitin领域的盛会，包括两位Nobel获奖者在内的60位全世界这个领域的顶级专家将作大会报告。这是一个与本领域专家交流的极好机会。欢迎参会，提交搞要，还有少量short talk机会。
生物加平台有幸受邀成为大会的媒体支持方！
为了配合本次大会的宣传，生物加组建了蛋白质泛素化研讨群
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8th International Conference
SUMO, Ubiquitin, UBL Proteins:
Implications for Human Diseases
Oct. 21-23, 2016 | Shanghai, China
March 18, 2016
Dear Friends,
The Eighth International Conference is dedicated to the 20th year celebration of the discovery of SUMO. In 1996, several laboratories reported a novel ubiquitin-like protein that was named Sentrin, GMP-1, PIC-1, and UBL1. This ubiquitin-like protein was shown to interact or modify FAS, RanGAP1, and PML. The SUMO conjugating and de-conjugating enzymes were quickly discovered and they dwarfed in size to the ubiquitin enzymes. Thus, the early workers in this field thought SUMO only modifies a limited number of substrates. However, we continue to be surprised by the versatility of the SUMO pathway. Thousands of SUMO substrates have now been reported and the biology of SUMO spans the entire spectrum of cell function and disease processes. The first decade of SUMO world depicted a parallel universe with the ubiquitin system; however, the second decade witnessed a collision of the SUMO and ubiquitin galaxies to create a new concept of SUMO-dependent ubiquitin-mediated protein degradation. The early biochemistry has entered cell biology and now explored at an organism level. Numerous disease processes and drug targets have been discovered in the field of ubiquitin and ubiquitin-like proteins. It is indeed a very exciting time! The Eight International Conference will continue our tradition of collegiality, discovery, and excellence. We will bring together world’s best scientists to gather in Shanghai to renew old friendships and to establish new ones.
Happy birthday SUMO!
Guo-Qiang Chen and Edward T.H. Yeh
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